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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SEC16A
All Species:
9.7
Human Site:
T1388
Identified Species:
23.7
UniProt:
O15027
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O15027
NP_055681.1
2179
233517
T1388
L
L
L
R
D
H
R
T
V
W
L
P
G
K
S
Chimpanzee
Pan troglodytes
XP_001171528
1350
147545
A643
W
G
H
A
L
L
L
A
S
K
M
D
S
R
T
Rhesus Macaque
Macaca mulatta
XP_001117942
1383
150489
G676
T
V
Y
Q
L
M
S
G
R
M
P
A
A
S
T
Dog
Lupus familis
XP_849192
2238
239022
T1442
L
L
L
Q
D
H
K
T
V
W
L
P
G
K
S
Cat
Felis silvestris
Mouse
Mus musculus
Q91XT4
1051
115505
C344
C
Q
Q
K
A
T
Q
C
L
K
S
E
T
P
G
Rat
Rattus norvegicus
Q75N33
1057
116878
T349
A
Q
C
L
K
S
E
T
P
G
S
R
D
S
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521275
2601
280417
T1579
L
L
L
R
D
H
K
T
V
W
L
P
G
K
S
Chicken
Gallus gallus
Q6AW68
929
102937
L222
P
V
Q
G
G
G
P
L
E
S
A
V
M
A
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_695457
2216
240508
E1408
I
A
D
L
L
L
K
E
H
R
S
V
W
L
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001096963
2021
220161
L1314
L
Y
E
D
R
Y
A
L
T
D
V
A
Q
K
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
60.8
56.6
68.5
N.A.
22.7
22.8
N.A.
50.6
20.5
N.A.
37.9
N.A.
20.2
N.A.
N.A.
N.A.
Protein Similarity:
100
61.4
58
75.5
N.A.
30.8
31.2
N.A.
60.3
28.3
N.A.
51.9
N.A.
34
N.A.
N.A.
N.A.
P-Site Identity:
100
0
0
86.6
N.A.
0
6.6
N.A.
93.3
0
N.A.
0
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
20
20
100
N.A.
20
13.3
N.A.
100
6.6
N.A.
13.3
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
0
10
10
0
10
10
0
0
10
20
10
10
10
% A
% Cys:
10
0
10
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
30
0
0
0
0
10
0
10
10
0
0
% D
% Glu:
0
0
10
0
0
0
10
10
10
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% F
% Gly:
0
10
0
10
10
10
0
10
0
10
0
0
30
0
10
% G
% His:
0
0
10
0
0
30
0
0
10
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
10
0
30
0
0
20
0
0
0
40
0
% K
% Leu:
40
30
30
20
30
20
10
20
10
0
30
0
0
10
0
% L
% Met:
0
0
0
0
0
10
0
0
0
10
10
0
10
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
0
0
0
0
10
0
10
0
10
30
0
10
20
% P
% Gln:
0
20
20
20
0
0
10
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
20
10
0
10
0
10
10
0
10
0
10
0
% R
% Ser:
0
0
0
0
0
10
10
0
10
10
30
0
10
20
30
% S
% Thr:
10
0
0
0
0
10
0
40
10
0
0
0
10
0
20
% T
% Val:
0
20
0
0
0
0
0
0
30
0
10
20
0
0
0
% V
% Trp:
10
0
0
0
0
0
0
0
0
30
0
0
10
0
0
% W
% Tyr:
0
10
10
0
0
10
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _